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Weston, FL, September 12, 2021 — The Week One NFL schedule is loaded with exciting matchups and with it the NFL Nation brings us the biggest keys to every game, along with bold picks and final score predictions.

For instance, the Buffalo Bills covered six home games last year, matching their total from the previous two years combined.

All eight of Arizona’s road games went “under” the total last season. But the “over” is 21-4-1 for Tennessee in the regular season in Ryan

Tannehill’s starts since he joined the team.

This is just the third time in the past 15 seasons that Jacksonville has been a road favorite in a division game.

Over the past two seasons, quarterbacks making their first career start are 18-6 ATS.

To read the complete report click here.

Trending Today: Checking The Boxes

There is a lot of information to process on opening week of the 2021 NFL season. How you it process will go a long way toward your bottom line.

For instance, 15 teams are expected to start a different quarterback today than they did in their season opener last year. Per ESPN Stats & Information, that ties for the 2nd most year-to-year QB change in the NFL modern era.

Furthermore, five games will feature matchups between quarterbacks making their first Week One start for their respective teams, the first time that has happened in NFL history.

Keep an eye on how the NY Giants fare now that RB Saquon Barkley in healthy and back in the starting lineup. In 11 career starts alongside Barkley, QB Daniel Jones has thrown 23 TD passes against nine interceptions.

And you can rest assured there will be a bunch of high rollers at Allegiant Stadium on Monday night. The game is the second-most in-demand ticket on the NFL’s secondary market with the price for a single ticket approaching $1,000.

Grinding Out The Profits: Birds Of Prey

From this week’s PLAYBOOK Football Newsletter: The Philadelphia Eagles allowed a season-high 65 sacks in 2020. They are also 1-12 ATS in domed stadiums the last five years.

Atlanta QB Matt Ryan is 11-2 SUATS in his home openers with the Falcons.

Connect the dots.

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